Why Weight Loss Gets Harder After 40 — And What Actually Works

Dr. Kelly Caperton • August 5, 2025

The Science of Midlife Metabolism — And How to Lose Weight Smarter, Not Harder

If you've hit your 40s and suddenly your go-to weight loss tricks aren't cutting it, you're not alone. Many women and men find that despite clean eating and regular workouts, the scale refuses to budge. But it's not your fault — your biology is simply changing. Here's why weight loss gets tougher with age, and what can actually move the needle.


Hormones Are Shifting

One of the biggest culprits is hormonal change. For women, perimenopause and menopause bring a natural decline in estrogen and progesterone, which can affect where fat is stored and how easily it's burned. Men also experience a gradual drop in testosterone, which can reduce muscle mass and slow metabolism. These hormonal shifts can trigger cravings, reduce energy, and interfere with sleep — all of which influence weight.


Muscle Mass Declines

Starting around age 30, we lose muscle mass at a rate of about 3-8% per decade. Less muscle means a slower resting metabolic rate. If you continue eating the same way you did in your 20s or 30s without adjusting for this change, weight gain is almost inevitable.


Insulin Sensitivity Drops

With age, our cells become less responsive to insulin, making it harder to regulate blood sugar. This can lead to more fat storage, particularly around the abdomen, and increase the risk for metabolic syndrome.


Stress and Sleep Take a Toll

Cortisol, the body's primary stress hormone, tends to rise with chronic stress and poor sleep. Elevated cortisol can contribute to fat retention, especially in the belly area, and sabotage weight loss efforts.


What Actually Works

1. Prioritize Protein and Resistance Training
Eating enough high-quality protein and lifting weights help preserve and build lean muscle, which keeps your metabolism more active.

2. Focus on Metabolic Health, Not Just Calories
At LifeSpaMD, we help patients target the root causes of weight gain, including hormonal imbalance, inflammation, and insulin resistance.

3. Consider Bioidentical Hormone Optimization
For eligible patients, bioidentical hormones can rebalance estrogen, progesterone, or testosterone levels, making it easier to manage weight and energy.

4. Use Targeted Medical Tools
We offer customized weight loss plans and cutting-edge tools like IgniteRF and peptide therapy to support fat loss and muscle tone without extreme diets or overtraining.

5. Sleep, Stress, and Longevity Habits
Optimizing sleep, reducing stress, and incorporating longevity-based lifestyle changes are essential for sustainable results.



You don’t need to eat less and exercise more — you need a smarter, hormone-informed strategy.

At LifeSpaMD, we specialize in longevity-first weight loss that works with your biology, not against it. Book a private consult to explore your personalized plan.

By Dr. Kelly Caperton July 30, 2025
Reclaim Strength, Sensation, and Control—No Surgery Required
By Dr. Kelly Caperton July 30, 2025
When it comes to non-surgical facial rejuvenation, FaceTite stands in a class of its own. As a physician specializing in longevity and medical aesthetics, I’ve seen firsthand how this advanced technology reshapes not only the face but also the future of skin tightening and fat reduction. What Is FaceTite? FaceTite is a minimally invasive treatment that uses radiofrequency-assisted lipolysis (RFAL) to contour, tighten, and rejuvenate the face and neck. It offers results comparable to a mini facelift—without the scars or downtime of surgery. The Power of Bipolar RF Energy Unlike older technologies that use monopolar energy (where current passes through the entire body), FaceTite uses bipolar radiofrequency. That means the energy is focused precisely between two electrodes: one placed beneath the skin and the other externally. This controlled energy delivery allows for: Precise skin heating : Stimulates collagen remodeling and tightens the fibroseptal network (FSN). Targeted fat coagulation : Safely reduces localized fat pockets under the chin and along the jawline. Thermal safety monitoring : Real-time temperature feedback helps ensure uniform, safe results. Who Is a Good Candidate? FaceTite is ideal for women and men in their 30s to 60s who want noticeable tightening and sculpting without going under the knife. It can treat: Jowls and lower face laxity Double chin and submental fullness Sagging neck skin Mild to moderate facial volume excess What to Expect from the Procedure Performed under local anesthesia, FaceTite involves tiny incisions (usually hidden behind the ears or under the chin). Using a slender probe, I deliver controlled RF energy beneath the skin while a complementary external electrode monitors the surface temperature. Most patients experience minimal discomfort and return to normal activities within a few days. Swelling and mild bruising can occur, but downtime is far less than traditional surgery. Results That Redefine Aging The beauty of FaceTite lies in its dual action: tightening skin and reducing fat simultaneously. Over the following 3 to 6 months, collagen production increases and the skin continues to contract—revealing a smoother, firmer, more sculpted appearance. As the first clinic in New Mexico to offer InMode technologies like FaceTite, LifeSpaMD is proud to lead the way in evidence-based, longevity-focused aesthetics. Interested in whether FaceTite is right for you? Schedule a consultation with me, Dr. Kelly Caperton, to explore your options for a sharper jawline, firmer skin, and more youthful profile—without surgery.